Side Effects - What you need to Know
The supplement resveratrol is naturally found in nature
& has been with us for a very long time - so long in fact one could say millions of years! In nature this compound is manufactured within plants as a protective agent,
& in times of stress a plant will produce this substance in large amounts, & it functions in the
same way as an antibiotic works within us. In nature it is called phytoalexin & is used as
protection to fight against pathogenic stressors.
This potent herb is found in the largest amounts in foods
such as peanuts (0.3 - 1.28mg per 180 grams of boiled peanuts) & grapes, but even so,
the concentrations are still way below the therapeutic dosage now suggested by recent research - unless you plan on
eating a LOT! Nowdays, we have formulations available that contain the appropriate amount of Trans Resveratrol all
in the convenience of a capsule. Generally speaking the optimal amount per
day of this supplement is not entirely known, but with time further research will provide us with a more exact
dosage.
In animal studies to date (which include
small mammals such as the humble mouse all the way up to the Rheuss monkey that shares a considerable amount of our
genetic makeup), this supplement was found to have a very positive effect against inflammation, & even cancer
as well. It was also found to actively promote cardiovascular health & lower blood sugar levels, with the most
relavent findings being the following;
In animal experiments thus far (including mammals ranging
from the humble mouse all the way up to the genetically similiar Rheuss monkey), this
compound has been found to have a very positive effect against
cancer and inflammation. It was found to lower blood sugar levels and
to promote cardiovascular health. The most pertinant findings pointed
to;
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A reduction in cholesterol levels
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Reducing vascular tissue
inflammation
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Assist with bone health, density, thickness,
mineral content & volume
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A lowering of cataract formation
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Enhanced nerve coordination & motor neuron
function
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Improved skeletal muscle & liver function,
whilst mitigating fatty tissue deposits
(These results were reported on July 3, 2008 by the US
National Institute on Aging, NIH News, U.S. Dept of Health and Human Services)
Side Effects that Have Been Associated with
Resveratrol
This bio active compound is still in its infancy
regarding clinical testing, but as time goes on more & more information will become available to us. It
has only been less than 10 years from the time that this supplement was discovered, but with what has been
discovered already about this amazing compound is very compelling indeed! Still, it s important to be a
little prudent at times, & this is why we have compiled the most common side effects below. Though
virtually all people who use this product only experience positive effects, at times some may experoence the
following;
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Upset
Tummy - This is generally the main concern for those who are deliberating whether
to use this product. The most common source of this active compound is from the
Japanese Knotwood plant. Whilst containing very high levels of Trans resveratrol, it also
contains small amounts of Emodin. Historically Emodin has been used
for treating constipation & pain
related diseases, not to mention its use medically as an effective tumor
inhibitor! As a rule this is only an issue if the purity is less
than 50% - the higher the percentage of refinement, the lower the amount of
emodin. Learn more about the effects of emodin & how it
works...
Solution: Our
formulation only contains a Trans Resveratrol of high purity - 98% & above. This means
that virtually ALL emodin is removed during processing - so no upset
tummies!
(extra alertness)
- Some individuals have initially had issues with sleeping, as the product
can increase alertness. Generally this quickly subsides within a period of 4 - 6 days, &
is thought to be a by - product of one's nervous system adjusting to the resveratrol
molecule within their system.
Solution:
If one takes the supplement earlier in
the day, & not prior to bed - then much of the sleep related issues will not be a
problem.
Minor Cold or Flu Like
Symtoms -
As mentioned earlier, this supplement activates the immune system. This can
at times trigger slight flu & cold like symptoms until such time that the body
acclimates. Initially this compoundcan suppress activity of B, T cells
& macrophages, as is reflected by a slight reduction in proliferation,
lymphokine & antibody
secretion. Anto RJ, Mukhopadadhyay A, Denning K, Aggarwal BB. Curcumin
(diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and
cytochrome C release: its suppression by ectopic expression of Bcl-2 and Bcl-xL.
Carcinogenesis.
2002;23:143–50
Solution:
Such symptoms generally balance out after
5 - 7 days, & tend to manifest only in individuals who are ingesting large doses
from the onset (1000mg & above). If daily doses are kept below this amount then there
will unlikely be any of the above mentioned
manifestations.
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As with most things in life,
moderation is the key. If you keep to the recommended dosage then virtually all of the above mentioned
side effects will likely not occur.
Listed below are further scientific studies outlining the safety & efficacy of this powerful
extract;
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